The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.
More Quotes from Francis Crick:
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.Francis Crick
By using polymers of different composition and assuming a triplet code one can deduce limited information about the composition of certain triplets.
Francis Crick
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.
Francis Crick
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis Crick
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
Francis Crick
It seems virtually certain that a single chain of RNA can act as messenger RNA, since poly U is a single chain without secondary structure.
Francis Crick
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Based on Topics: Majority & Minority QuotesBased on Keywords: ambiguous, amino, triplets, unclear
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