For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.
More Quotes from Francis Crick:
It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule.Francis Crick
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis Crick
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
Francis Crick
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
Francis Crick
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
Francis Crick
Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.
Francis Crick
Readers Who Like This Quotation Also Like:
Based on Keywords: simplicityIf we win, we'll make history, and I'll serve you on the Agriculture Committee.
George Nethercutt
We need to listen to consumers' needs.
Sumner Redstone
I'm susceptible to that sort of thing - to walls and flowers. You can probably get something more from a wall than a person sometimes. It's just put somewhere.
Ray Davies