If poly A is added to poly U, to form a double or triple helix, the combination is inactive.
More Quotes from Francis Crick:
By using polymers of different composition and assuming a triplet code one can deduce limited information about the composition of certain triplets.Francis Crick
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
Francis Crick
Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to be a complete artefact and is very probably closely related to genuine protein synthesis.
Francis Crick
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
Francis Crick
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
Francis Crick
We've discovered the secret of life.
Francis Crick
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