The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed. To really cure depression, we probably need to find new treatments that can remove the silencer molecules.
Eric Nestler Quotes on Brain (3 Quotes)
Our study provides insight into how chronic stress triggers changes in the brain that are much more long-lived than the effects of existing antidepressants.
One of the cardinal features of addiction is how long-lived it is, ... A key question in the field has been By what mechanisms do drugs of abuse cause changes in the brain that last this long.
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