First, ... those suffering from porphyria look severely anemic because their hemoglobin is not being utilized efficiently and their blood is not as oxygenated as it should be. Second, the porphyrin rings that cannot do their job are deposited in the subcutaneous fat beneath the skin. The chemical is photosensitive, and in sunlight it can release electrons that damage the skin and may cause severe blistering -- hence the vampire's fear of sunlight.
Quotes about hemoglobin (3 Quotes)
Only certain donors qualify for this method. It's based mostly on height, weight and hemoglobin levels.
That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.