Quotes about genome (16 Quotes)


    Just as DNA chips revolutionized genome analysis, we hope to make cell chips (self-assembled arrays of cells on a thumbnail-sized chip) using our DNA-based cell adhesion strategy. Cell chips could be used as biosensors for detecting the presence of pathogens, or for drug screening, just to name of a few of the many possibilities.

    The overall view of the human genome project has been one of great excitement and positive press, but there are people who have concerns that are quite reasonable, and they are frightened of things they don't understand.


    It is important to consider whether the sample size selected by the Environmental Genome Project will provide sufficient power to discover most alleles relevant to gene-environment interactions.

    In the Human Genome Project, we at least knew what the endpoint would be. It was just a technology question of how to get there. In our case, we are asking questions that no one knows the answer to because stem cell research is so new.


    Why do people believe that there are dangerous implications of the idea that the mind is a product of the brain, that the brain is organized in part by the genome, and that the genome was shaped by natural selection?


    One of the responsibilities faced by the Environmental Genome Project is to provide the science base upon which society can make better informed risk management decisions.

    Sometimes it is claimed by those who argue that race is just a social construct that the human genome project shows that because people share roughly 99% of their genes in common, that there are no races. This is silly.

    Having a sequence of the human genome is good, but our ability to interpret it was limited. The mouse sequence provides, for the first time, an ability to determine what matters and what doesn't in the human genome.

    Having identified these previously unknown mutations in key cancer causing genes, we will hopefully enable the development of small molecules and antibodies to regulate their abnormal function and thus inhibit the growth of cancerous cells. This collaborative study exemplifies exactly what our coalition was formed to do -- leverage our individual institution's expertise to collectively discover new druggable targets through genome sequencing and functional genomic analysis.


    During this period, I became interested in how the new techniques of cloning and sequencing DNA could influence the study of genetics and I was an early and active proponent of the Human Genome Sequencing Project.

    In the genomics world, we are supporting Craig Venter's original vision of getting an ability to have gene sequencing occur for the masses. While we have a single genome sequenced, the real benefits for humanity come when there are tens of thousands of genomes sequenced and the computing power available today can correlate certain sequences with certain diseases or drug interactions.

    While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

    This is the bizarre thing. This exact period I'm writing about is also a period of the most extraordinary scientific and technological achievement, from the mapping of the human genome to the creation of the internet. It seems paradoxical that there should be this proliferation of mumbo jumbo at a time of such immense change and upheaval, but that may be a partial explanation for it.



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