That would make addiction more inheritable than diseases we commonly think of as genetic, such as adult onset diabetes or common hypertension,
More Quotes from Eric Nestler:
Without BDNF in the circuit, an animal can't learn that a social stimulus is threatening and respond appropriately.Eric Nestler
Our study provides insight into how chronic stress triggers changes in the brain that are much more long-lived than the effects of existing antidepressants.
Eric Nestler
The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed. To really cure depression, we probably need to find new treatments that can remove the silencer molecules.
Eric Nestler
The social-defeat process induced production of BDNF in the reward circuit. Without BDNF in the circuit, an animal can't learn that a social stimulus is threatening and respond accordingly.
Eric Nestler
Our study provides a fundamentally new level of analysis by which we can better understand the actions of cocaine in brain-reward regions at the molecular level. It also points to new potential treatments for addiction.
Eric Nestler
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