The implication, albeit a speculative one, is that those activity patterns in young adults are the foothold onto which Alzheimer's disease forms.
More Quotes from Randy Buckner:
It may be the normal cognitive function of the brain that leads to Alzheimer's later in life. This was not a relationship we had even considered.Randy Buckner
The default activity patterns of the brain may, over many years, augment a metabolic- or activity-dependent cascade that participates in Alzheimer's disease pathology. The regions of the brain we tend to use in our default state when we are young are very similar to the regions where plaques form in older people with Alzheimer's disease. This is quite a remarkable convergence that we did not expect.
Randy Buckner
We appear to use memory systems often in our default states. This may help us to plan and solve problems. Maybe it helps us be creative. But it may also have metabolic consequences.
Randy Buckner
The regions of the brain we tend to use in our default state when we are young are very similar to the regions where plaques form in older people with Alzheimer's disease.
Randy Buckner
We've been surprised to find out how malleable the brain is.
Randy Buckner
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