For many children current therapies are curative. But the price they pay in long-term side effects is far too high.
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There's a desperate need for new approaches. The success in pediatric oncology has been made with drugs that have been around for 30 years.Peter Adamson
Our ability to move ahead has waned. Overcoming the most difficult cancers with higher doses is not likely to succeed anymore.
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Adamson feels that drug developers are unreasonably concerned about rare events. The reality is children tolerate phase I therapy new agents being tested to find the best dosage and possible side-effects as well as or better than adults, ... Once the initial studies are done that is, phase I trials in adults study should begin in children.
Peter Adamson
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