Using the Bayesian approach, it is natural to do continuous updating as information accrues. This characteristic makes it possible for us to build adaptive designs in clinical trials.
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The American Cancer Society has it right. I do think mammograms save lives.Donald Berry
All seven groups concluded that the decline in the rate of death from breast cancer is a combination of screening and therapy, and not restricted to one or the other.
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Doctors want to be able to design trials to look at multiple potential treatment combinations and use biomarkers to determine who is responding to what medication. At the end of the day, when they enroll the last patient in the study they want to be able
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Our biggest challenge is to convince the regulators that we are not throwing the baby out with the bathwater by using a Bayesian approach. It is rigorous and we are not losing science by using it.
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This is the first time that a study does it right in asking the effects of screening separate from therapy.
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I'd do it again if I had to. We made it here all safely. That's the main thing. (Claudia and Joe) have been a blessing. I just wished they had lived a little bit closer.
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